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  1. Abstract

    The planets’ gravitational interaction causes rhythmic changes in Earth’s orbital parameters (also called Milanković cycles), which have powerful applications in geology and astrochronology. For instance, the primary astronomical eccentricity cycle due to the secular frequency term (g2g5) (∼405 kyr in the recent past) utilized in deep-time analyses is dominated by the orbits of Venus and Jupiter, i.e., long eccentricity cycle. The widely accepted and long-held view is that (g2g5) was practically stable in the past and may hence be used as a “metronome” to reconstruct accurate geologic ages and chronologies. However, using state-of-the-art integrations of the solar system, we show here that (g2g5) can become unstable over long timescales, without major changes in, or destabilization of, planetary orbits. The (g2g5) disruption is due to the secular resonanceσ12= (g1g2) + (s1s2), a major contributor to solar system chaos. We demonstrate that entering/exiting theσ12resonance is a common phenomenon on long timescales, occurring in ∼40% of our solutions. Duringσ12-resonance episodes, (g2g5) is very weak or absent and Earth’s orbital eccentricity and climate-forcing spectrum are unrecognizable compared to the recent past. Our results have fundamental implications for geology and astrochronology, as well as climate forcing, because the paradigm that the long eccentricity cycle is stable, dominates Earth's orbital eccentricity spectrum, and has a period of ∼405 kyr requires revision.

     
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  2. Free, publicly-accessible full text available February 1, 2025
  3. Abstract Each year, bovine respiratory disease (BRD) results in significant economic loss in the cattle sector, and novel metabolic profiling for early diagnosis represents a promising tool for developing effective measures for disease management. Here, 1 H-nuclear magnetic resonance ( 1 H-NMR) spectra were used to characterize metabolites from blood plasma collected from male dairy calves (n = 10) intentionally infected with two of the main BRD causal agents, bovine respiratory syncytial virus (BRSV) and Mannheimia haemolytica (MH), to generate a well-defined metabolomic profile under controlled conditions. In response to infection, 46 metabolites (BRSV = 32, MH = 33) changed in concentration compared to the uninfected state. Fuel substrates and products exhibited a particularly strong effect, reflecting imbalances that occur during the immune response. Furthermore, 1 H-NMR spectra from samples from the uninfected and infected stages were discriminated with an accuracy, sensitivity, and specificity ≥ 95% using chemometrics to model the changes associated with disease, suggesting that metabolic profiles can be used for further development, understanding, and validation of novel diagnostic tools. 
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    Free, publicly-accessible full text available December 1, 2024
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  5. Free, publicly-accessible full text available June 1, 2024
  6. Abstract

    Reliable studies of the long-term dynamics of planetary systems require numerical integrators that are accurate and fast. The challenge is often formidable because the chaotic nature of many systems requires relative numerical error bounds at or close to machine precision (∼10−16, double-precision arithmetic); otherwise, numerical chaos may dominate over physical chaos. Currently, the speed/accuracy demands are usually only met by symplectic integrators. For example, the most up-to-date long-term astronomical solutions for the solar system in the past (widely used in, e.g., astrochronology and high-precision geological dating) have been obtained using symplectic integrators. However, the source codes of these integrators are unavailable. Here I present the symplectic integratororbitN(lean version 1.0) with the primary goal of generating accurate and reproducible long-term orbital solutions for near-Keplerian planetary systems (here the solar system) with a dominant massM0. Among other features,orbitN-1.0includesM0’s quadrupole moment, a lunar contribution, and post-Newtonian corrections (1PN) due toM0(fast symplectic implementation). To reduce numerical round-off errors, Kahan compensated summation was implemented. I useorbitNto provide insight into the effect of various processes on the long-term chaos in the solar system. Notably, 1PN corrections have the opposite effect on chaoticity/stability on a 100 Myr versus Gyr timescale. For the current application,orbitNis about as fast as or faster (factor 1.15–2.6) than comparable integrators, depending on hardware.1

    The orbitN source code (C) is available athttp://github.com/rezeebe/orbitN.

     
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  7. Free, publicly-accessible full text available June 1, 2024
  8. Free, publicly-accessible full text available July 23, 2024
  9. Climate change is leading to substantial global thermal changes, which are particularly pronounced in polar regions. Few studies have examined the impact of heat stress on reproduction in Antarctic terrestrial arthropods, specifically how brief, extreme events may alter survival. We observed that sublethal heat stress reduces male fecundity in an Antarctic mite, yielding females that produced fewer viable eggs. Females and males collected from microhabitats with high temperatures showed a similar reduction in fertility. This impact is temporary, as indicated by recovery of male fecundity following return to cooler, stable conditions. The diminished fecundity is likely due to a drastic reduction in the expression of male-associated factors that occur in tandem with a substantial increase in the expression of heat shock proteins. Cross mating between mites from different sites confirmed that heat-exposed populations have impaired male fertility. However, the impact on fertility declines with time when the mites are allowed to recover under less stressful conditions, suggesting that the negative effects are transient. Modeling indicated that heat stress is likely to reduce population growth and that short bouts of non-lethal heat stress could have substantial effects on local populations of Antarctic arthropods. 
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    Free, publicly-accessible full text available September 1, 2024